1. Noun

   muscle stiffness (esp. in shoulders)

   乳房にしこりがあります。

2. lump (in tissue, esp. breast); swelling; hardening; lesion

   MedicineUsually written using kana alone

3. lingering discomfort; uneasiness; bad aftertaste; unpleasant feeling

   Usually written using kana alone

Also written 凝【しこり】shikori、痼り【しこり】shikori、痼【しこり】shikori